Hill Dickinson Stadium will host its first international men’s football fixture in March.
Everton’s home is set to welcome a World Cup warm-up match between Scotland and the Ivory Coast on Tuesday, March 31 as part of the ‘Road to 26’ series.
Nathan Patterson will step out at his current stomping ground for the Tartan Army alongside familiar faces from across the Premier League in both squads.
Napoli’s Scott McTominay and Aston Villa captain John McGinn are also in line to feature for Steve Clarke’s side against the three-time Africa Cup of Nations winners.
It is the latest high-profile event to take place at Hill Dickinson Stadium, which will also host Euro 2028 matches and is a potential 2035 Women’s World Cup venue.
The waterfront arena at Bramley-Moore Dock has already staged a Rugby League Ashes series and is set to welcome the sport’s Magic Weekend later this year.
Scotland head coach Steve Clarke added: “We’re pleased to confirm Ivory Coast as our second opponents for the March international window, following on from Japan’s visit to Glasgow.
“We wanted to face African opposition before we play Morocco in the summer, and I’m sure Ivory Coast will give us a really stern test.
“It will also be good to play at the Hill Dickinson Stadium in Liverpool.
“The supporters will enjoy the opportunity to visit the new stadium.”
Ivory Coast head coach Emerse Fae added: “Coming to Liverpool to face Scotland will be an excellent test for us against European opposition ahead of the FIFA World Cup.
“It is a great opportunity to measure our level against players from top clubs, many of whom we know well from the Premier League.
“We are very happy to play this friendly in such a fantastic atmosphere, in a wonderful stadium, in front of passionate Scottish fans.
“We are really excited to be there.”