Alisson is set to miss Liverpool’s Premier League clash with Brentford.
The Brazil international was sidelined for last weekend’s win over Burnley with flu but Jurgen Klopp confirmed on Friday that he was set to return to action.
However Alisson has rejoined the Anfield casualty list with muscle injury picked up in training ahead of the trip to the Brentford Community Stadium.
A timescale on the Reds’ goalkeeper’s latest absence remains undetermined but will see Caoimhin Kelleher retain his starting place for a second week.
Klopp had already confirmed that the Irishman will be starting in the Carabao Cup final against Chelsea irrespective of Alisson’s potential availability.
News of the first-choice stopper’s setback is yet another blow for Klopp’s side, already contending with several high-profile absences ahead of Wembley.
Trent Alexander-Arnold is set to miss several weeks while the cup final will likely arrive too soon for Dominink Szoboszlai to be back in contention.
Beyond the established pair, Thiago Alcantara’s Liverpool career appears to be all but over after suffering a relapse during his long-awaited comeback.
The Spain midfielder is out of contract this summer and risks having played his final game for the club if he cannot recover before the end of the season.
Liverpool will, however, be able to call on Mohamed Salah for their trip to west London after his return to training earlier this week placed him in contention.