Everton could lose Seamus Coleman for up to six months following his leg break.
Coleman underwent surgery to repair the tibia and fibia in his right leg on Saturday following the horrific injury suffered on Republic of Ireland duty.
The Blues’ right-back was floored by a challenge by Swansea’s Neil Taylor midway through his country’s World Cup qualifier with Wales in Dublin.
A lengthy lay-off period is anticipated from the injury which mirrors one sustained by former team mate Bryan Oviedo against Stevenage in 2014.
Ronald Koeman has vowed that Everton will help him through a lengthy road to recovery.
He said: “I haven’t been able to speak to Seamus as yet and I hope to do so this afternoon.
“But he will be aware that the thoughts of his teammates, the coaching staff, everyone at the club and all Evertonians are with him at this time.
“No-one ever wishes to see something like this happen to any player, much less one of our own.
“The medical staff here at Everton are in contact with the medical staff of the Republic of Ireland and we will continue to liaise closely.
“Seamus will face a lengthy recovery period and we will support him throughout this.
“He is a really strong character and he has a great family around him and we, his extended family at Everton, will be here for him to help him get through this over the coming days, weeks and months.”